Search Result

Search Results for " e cadherin "

Targets

Apoptosis Phosphatase Gamma-secretase Immunology/Inflammation related

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T13410	ZLDI-8		Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related
	ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
T3144	BML-284	Wnt agonist 1	Wnt/beta-catenin
	BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.		Wnt/beta-catenin
T8820	BML-284 hydrochloride	BML-284 HCL,Wnt agonist 1 HCL	Wnt/beta-catenin
	BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.		Wnt/beta-catenin
T4252	ML327		c-Myc , Autophagy
	ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).		c-Myc , Autophagy
T78532	HDAC-IN-55		Others
	HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1].		Others
T81058	SWELYYPLRANL-NH2 TFA
	SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 μM and 0.09 μM, respectively...
T81059	SWELYYPLRANL-NH2
	SWELYYPLRANL-NH2 is a dual antagonist of E-cadherin and N-cadherin, effectively inhibiting the binding of phage clones to both E-cad/Fc and N-cad/Fc chimeric proteins with IC50 values of 0.7 μM and 0.09 μM, respectively....
T60639	SLEC-11
	SLEC-11 emerged as a synthetic lethal(SL) lead in E-cadherin-deficient cells which has potential for the treatment of gastric cancer.
T41169	P21d hydrochloride
	P21d hydrochloride is a potent and selective breast tumor Ki nase (Brk) inhibitor (IC50 = 30 nM). Exhibits >650-fold selectively for Brk over Aurora B Ki nase and Lck. Downregulates SNAIL protein, restores E-cadherin exp...
T62822	CT1-3
	CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
T69685	AGPS-IN-2i		MMP
	AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferat...		MMP

Compounds

ZLDI-8

T13410

Synonym:

Target: Apoptosis, Phosphatase, Gamma-secretase, Immunology/Inflammation related

BML-284

T3144

Synonym: Wnt agonist 1

Target: Wnt/beta-catenin

BML-284 hydrochloride

T8820

Synonym: BML-284 HCL,Wnt agonist 1 HCL

Target: Wnt/beta-catenin

ML327

T4252

Synonym:

Target: c-Myc, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03762	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
TMPY-04041	E-Cadherin/Cadherin-1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.4 kDa and the accession number is Q9R0T4.
TMPY-03244	E-Cadherin/Cadherin-1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 103.8 kDa and the accession number is Q9R0T4.
TMPY-05052	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62 kDa and the accession number is A0A0U2ZQU7.
TMPY-05656	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.1 kDa and the accession number is P12830-1.
TMPK-00509	E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelia...
TMPY-02137	E-Cadherin/Cadherin-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	E-Cadherin/Cadherin-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78 kDa and the accession number is P09803.
TMPH-02307	Vinculin Protein, Human, Recombinant (GST)	Human	E. coli
	Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play impor...
TMPH-00331	ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc)	Candida albicans	E. coli
	Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans...
TMPK-01306	CDH3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove...
TMPK-00800	CDH3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove...
TMPK-00851	CDH3 Protein, Human, Recombinant (aa 108-654, His)	Human	HEK293 Cells
	Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove...
TMPH-01218	DSP Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the...
TMPY-00610	RAB2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and i...
TMPH-02539	MGAT3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannos...
TMPY-03795	EIF5A2 Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPH-02217	SMARCA4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPK-01424	Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01423	Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-E01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01544	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01452	HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01541	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01514	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01545	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...